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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0020 | AMG 837 calcium hydrate | GPR | |
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM). | |||
T14215 | AMG 837 sodium salt | Others | |
AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agoni... | |||
T14216 | AMG 837 | Others | |
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex... | |||
T62848 | AMG 837 hemicalcium | ||
AMG 837 hemicalcium is a potent, orally active GPR40/FFA1 partial agonist. AMG 837 hemicalcium inhibits the specific binding of [3H]AMG 837 to the human FFA1 receptor (pIC50: 8.13). insulin secretion and reduced glucose ... |